Certified Clinical Research Associate (CCRA) Practice Exam 2026 – All-in-One Guide to Master Your Certification!

The purpose of a Data and Safety Monitoring Board (DSMB) primarily revolves around ensuring the safety of subjects involved in a clinical trial. A DSMB is an independent group of experts who monitor data and patient safety throughout the duration of a clinical study. Their responsibilities include reviewing interim data to assess the safety of participants, evaluating the efficacy of the treatment being studied, and ensuring that the trial continues to be ethical and safe for participants.

The DSMB has the authority to recommend the continuation, modification, or termination of the trial based on these assessments. By focusing specifically on the safety of trial participants, the DSMB plays a crucial role in protecting patient welfare, which is a fundamental ethical consideration in clinical research. This oversight helps to minimize risks and addresses any potential issues related to patient safety proactively.