Certified Clinical Research Associate (CCRA) Practice Exam 2025 – All-in-One Guide to Master Your Certification!

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What defines a Global Assessment Variable in clinical trials?

A variable that summarizes safety data

A single scale integrating various objectives and impressions

A Global Assessment Variable in clinical trials is characterized by its capacity to integrate various objectives and impressions into a single scale. This integration allows for a comprehensive evaluation of the overall effect of an intervention, taking into account multiple dimensions of a patient's health status or response to treatment.

In clinical research, being able to capture a holistic view of an intervention’s impact is crucial, as it provides insights beyond just specific endpoints or outcomes. Such a scale is particularly valuable in studies assessing subjective experiences, such as quality of life or overall satisfaction, where various factors contribute to the overall assessment.

While the other options present relevant concepts in clinical trials, they do not precisely define what a Global Assessment Variable entails. Summarizing safety data or measuring trial efficiency focuses on narrower aspects, and discrete outcome variables pertain to specific measurements rather than an integrated view. Thus, the essence of the Global Assessment Variable is its role in synthesizing diverse data into a singular, interpretable metric that reflects a broader understanding of treatment effects.

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A statistical measure of trial efficiency

A discrete outcome variable from trial subjects

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